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ISCMR Scientific Article Prize

Mojtaba Heydari (2019-2020 WINNER)
Published On 1/1/2019
Zare R, Nadjarzadeh A, Zarshenas MM, Shams M, Heydari M. (2019). "Efficacy of cinnamon in patients with type II diabetes mellitus: A randomized controlled clinical trial". Clinical Nutrition, 38(2), 549-56. doi.org/10.1016/j.clnu.2018.03.003.
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Vincent Chung (2019-2020 HONORABLE MENTION)
Published On 1/1/2019
Chung VCH, Wong CHL, Wu IXY, Ching JYL, Cheung WKW, Yip BHK, Chan KL, Cheong PK, Wu JCY. (2019). "Electroacupuncture plus on‐demand gastrocaine for refractory functional dyspepsia: Pragmatic randomized trial". Journal of Gastroenterology & Hepatology, 34 (12):2077-85. doi.org/10.1111/jgh.14737.
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Meaghan Coyle (2019-2020 HONORABLE MENTION)
Published On 1/1/2019
Coyle ME, Yu JJ, Zhang AL, Jones L, Xue CC, Lu C. (2020). "Patient experiences of using Chinese herbal medicine for psoriasis vulgaris and chronic urticaria: a qualitative study". Journal of Dermatological Treatment, 31(4): 352-8. doi.org/10.1080/09546634.2019.1591580.
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Jerome Sarris (2019-2020 WINNER)
Published On 1/1/2019
Sarris J, Murphy J, Stough C, Mischoulon D, Bousman C, MacDonald P, Adams L, Nazareth S, Oliver G, Cribb L, Savage K, Menon R, Chamoli S, Berk M, Ng Ch, Byrne GJ. (2019). "S-Adenosylmethionine (SAMe) monotherapy for depression: an 8-week double-blind, randomised, controlled trial". Psychopharmacology, 237: 209-18. doi.org/10.1007/s00213-019-05358-1.
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Caroline Smith (2019-2020 HONORABLE MENTION)
Published On 1/1/2019
Smith CA, Armour M, Shewamene Z, Tan HY, Norman RJ, Johnson NP. (2019). "Acupuncture performed around the time of embryo transfer: a systematic review and meta-analysis". Reproductive BioMedicine Online, 48(3):364-79. doi.org/10.1016/j.rbmo.2018.12.038.
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Dennis Anheyer (2018-2019 WINNER)
Published On 1/1/2018
Anheyer, D., Haller, H., Barth, J., Lauche, R., Dobos, G., & Cramer, H. (2017). "Mindfulness-based stress reduction for treating low back pain: a systematic review and meta-analysis". Annals of Internal Medicine, 166(11), 799-807. doi:10.7326/M16-1997.
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Nadine Ijaz (2018-2019 HONORABLE MENTION)
Published On 1/1/2018
Ijaz N, Rioux J, Elder C, Weeks J (2019). "Whole Systems Research Methods in Health Care: A Scoping Review". Journal of Alternative and Complementary Medicine. 2019. Mar;25(S1):S21-S51. doi:10.1089/acm.2018.0499.
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Elizabeth Papathanassoglou (2018-2019 HONORABLE MENTION)
Published On 1/1/2018
Papathanassoglou E, Hadjibalassi M, Lambrinou E, Papastavrou E, Paikousis L, Kyprianou T. (2018) "Effects of an Integrative Nursing Intervention on Pain in Critically Ill Patients: A Pilot Clinical Trial. American", Journal of Critical Care. 27(3):172-185.
doi.org/10.4037/ajcc2018271.
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Lesley Ward (2017-2018 WINNER)
Published On 1/1/2017
Ward L, Stebbings S, Athens J, Cherkin D, Baxter GD. "Yoga for the management of pain and sleep in rheumatoid arthritis: a pilot randomized controlled trial". Musculoskeletal Care. 2018;16:39-47. doi.org/10.1002/msc.1201
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Suzie Zick (2017-2018 HONORABLE MENTION)
Published On 1/1/2017
Zick SM, Sen A, Wyatt GK, Murphy SL, Arnedt JT, Harris RE. "Investigation of 2 Types of Self-administered Acupressure for Persistent Cancer-Related Fatigue in Breast Cancer Survivors: A Randomized Clinical Trial". JAMA Oncology. 2016;2(11):1470-1476.
doi:10.1001/jamaoncol.2016.1867.
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Somnath D. Bhinge (2017-2018 HONORABLE MENTION)
Published On 1/1/2017
Bhinge SD, Bhutkar, MA, Randive DS, Wadkar GH, Todkar SS, Kakade PM, Kadam PM. "Formulation development and evaluation of an antimicrobial polyherbal gel". Annales Pharmaceutiques Francaises. 2017;75(5): 348-358. doi.org/10.1016/j.pharma/2017.04.006.
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Nadine Ijaz (2016-2017 WINNER)
Published On 1/1/2016
Ijaz N, Boon H, Muzzin L, Welsh S. "State risk discourse and the regulatory preservation of traditional medicine knowledge: The case of acupuncture in Ontario, Canada." Social Science & Medicine. 170 (2016): 97-105. dx.doi.org/10.1016/j.socscimed.2016.08.037.
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Holger Cramer (2016-2017 HONORABLE MENTION)
Published On 1/1/2016
Cramer H, Rabsilber S, Lauche R, Kümmel S, Dobos G. "Yoga and meditation for menopausal symptoms in breast cancer survivors - a randomized controlled trial". Cancer. 2015; 121(13):2175–84. doi.org/10.1016/j.maturitas.2017.05.008.
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Beverly de Valois (2016-2017 HONORABLE MENTION)
Published On 1/1/2016
de Valois B, Asprey A, Young T. "'The Monkey on Your Shoulder': A Qualitative Study of Lymphoedema Patients’ Attitudes to and Experiences of Acupuncture and Moxibustion". Evidence-Based Complementary and Alternative Medicine. 2016. doi:10.1155/2016/4298420.
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Claudia Witt (2015-2016 WINNER)
Published On 1/1/2015
Witt CM, Außerer O, Baier S, Heidegger H, Icke K, Mayr O, Mitterer M, Roll S, Spizzo G, Scherer A, Thuile C, Wieser A, Schützler L. "Effectiveness of an additional individualized multi-component complementary medicine treatment on health-related quality of life in breast cancer patients: a pragmatic randomized trial". Breast Cancer Research and Treatment. 2015, Jan;149(2):449-60. doi.org/10.1007/s10549-014-3249-3.
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Pamela E. Jeter (2015-2016 HONORABLE MENTION)
Published On 1/1/2015
Jeter PE, Haaz Moonaz S, Bittner AK, Dagnelie G (2015) "Ashtanga-Based Yoga Therapy Increases the Sensory Contribution to Postural Stability in Visually-Impaired Persons at Risk for Falls as Measured by the Wii Balance Board: A Pilot Randomized Controlled Trial". PLoS ONE 10(6): e0129646. doi.org/10.1371/journal.pone.0129646.
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Sunita Vohra (2015-2016 HONORABLE MENTION)
Published On 1/1/2015
Vohra S, Shamseer L, Sampson M, Bukutu C, Schmid C, Tate R, Nikles J, Zucker D, Kravitz R, Guyatt G, Altman D, Moher D. "CONSORT Extension for reporting N-of-1 Trials (CENT) 2015 Statement". British Medical Journal. 2015; 350:h1738..
doi.org/10.1016/j.jclinepi.2015.05.004.
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Tobias Sundberg (2014-2015 WINNER)
Published On 1/1/2014
Sundberg T, Hagber L, Zethraeus N, and Falkenberg T. "Integrative medicine for back and neck pain: Exploring cost-effectiveness alongside a randomized clinical pilot trial". European Journal of Integrative Medicine. 2014, 6:29–38.
doi.org/10.1016/j.eujim.2013.09.001
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Dr. George Lewith Poster Prize

Dennis Muñoz-Vergara (2022 WINNER)
Published On 5/27/2022
The effects of a single bout of high- and moderate-intensity yoga exercise on circulating inflammatory mediators: a pilot feasibility study.

Congratulations to Dennis Muñoz-Vergara, Brigham and Women's Hospital, Harvard Medical School (USA) winner of the ISCMR Dr. George Lewith Poster Prize for the best trainee posters at the 2022 International Congress on Integrative Medicine and Health.
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Larisa Barnes (2019 WINNER)
Published On 1/1/2019
University of Sydney (Australia) - Australian women’s health literacy and complex decision – making to use complementary medicines in pregnancy and lactation – A qualitative investigation
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Melanie Desiree Höxtermann (2019 RUNNER UP)
Published On 1/1/2019
University of Duisburg-Essen (Germany) - Cancer, sleep problems and mind-body medicine use: A nationally representative survey
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Jiyoon Won (2019 RUNNER UP)
Published On 1/1/2019
Kyung Hee University (Republic of Korea) - Adverse events given in participant information leaflets of randomized sham – controlled trials of acupuncture
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Mingkun Yu (2019 HONORABLE MENTION)
Published On 1/1/2019
Beijing University of Chinese Medicine (China) - Characteristics of Methodological Studies on Participant Retention in RCT of TCM and Conventional Medicine in China
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Chun-li Lu (2019 HONORABLE MENTION)
Published On 1/1/2019
Beijing University of Chinese Medicine (China) - Evidence base of clinical studies of fasting therapy: a bibliometric analysis
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Isabel Roth (2018 WINNER)
Published On 1/1/2018
UTHealth School of Public Health (Houston, USA) - Employing Evidence in Evaluating Complementary Therapies: Findings from an Ethnography of Integrative Pain Management at a Large Urban Pediatric Hospital
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Dennis Anheyer (2018 RUNNER UP)
Published On 1/1/2018
University of Duisburg-Essen (Germany) - Yoga for headache in adolescents: a multicenter randomized controlled trial
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Kristen Wright (2018 RUNNER UP)
Published On 1/1/2018
Oregon Health & Science University (USA) - Multidisciplinary approach to the development of a rational phytotherapeutic from Centella asiatica
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Ruixue Hu (2018 HONORABLE MENTION)
Published On 1/1/2018
Beijing University of Chinese Medicine (China) - Adverse events and adverse drug reactions of a patent Chinese herbal medicine: Inconsistency of data from literatures and real-world state monitoring
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Heidemarie Haller (2018 HONORABLE MENTION)
Published On 1/1/2018
University of Duisburg-Essen (Germany) - Mindfulness-based interventions for DSM-5 anxiety disorders - a systematic review and meta-analysis
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Li Qiong Wang (2016 WINNER)
Published On 1/1/2016
Beijing University of Chinese Medicine (Beijing, China) - Comparison Between English And Chinese Publications Of Randomized Clinical Trials On Acupuncture.

Li-Qiong Wang, Chun-Xiang Su, Yu-Yi Wang, Guo-Yan Yang, Ning Liang, Jian-Ping Liu
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Jiaxing Tian (2016 RUNNER UP)
Published On 1/1/2016
China Academy of Chinese Medical Sciences (Beijing, China) - Clinical Observations On The Dose- Effect Relationship In T2dm Based On Dosage Changing In Different Herbal Medicine Of Gegenqinlian Decoction

Jiaxing Tian, Fengmei Lian, Xiaolin Tong
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Andrew Flower (2016 RUNNER UP)
Published On 1/1/2016
University of Southampton (Southampton, UK) - The Ruti Trial: A Multi-Centred, 16 Week, Randomised, Double Blind, Placebo Controlled, Feasibility Study Of Chinese Herbal Medicine (CHM) For Women With Recurrent Urinary Tract Infections (Rutis)
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Elizabeth Adler (2016 HONORABLE MENTION)
Published On 1/1/2016
University of California (San Francisco, USA)
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Kirstin Jeuger (2016 HONORABLE MENTION)
Published On 1/1/2016
University of North Carolina (Chapel Hill, USA)
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Amber Fyfe-Johnson (2013 WINNER)
Published On 1/1/2013
Penny George Institute for Health and Healing Minneapolis (USA)- Effects of Inpatient Integrative Medicine on Pain and Anxiety in an Acute Cardiovascular Population
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Seunghoon Lee (2013 RUNNER UP)
Published On 1/1/2013
Kyunghee University (Korea) - Randomized Double Blind Clinical Trial of Ojeoksan Products Extracted though Different Methods for Low Back Pain
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Gaelle Desbordes (2013 RUNNER UP)
Published On 1/1/2013
Boston University (USA) - Assessment of Autonomic Tone at Rest and during Mediation in a Longitudinal Study of an Eight week Meditation Intervention
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Donya Nemati (2022 RUNNER UP)
Published On 5/27/2022
Theory-based Investigation of Behavioral Determinants to Perform Self-administered Knee Massage in a Self-management Routine for Knee Osteoarthritis.

Congratulations to Donya Nemati, Indiana University (USA), runner up in the ISCMR Dr. George Lewith Poster Prize for the best trainee posters at the 2022 International Congress on Integrative Medicine and Health.
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Jill Cole (2022 RUNNER UP)
Published On 5/27/2022
Hospital-Based Massage Therapy Interventions in Patients with Cancer: A Retrospective Chart Review.

Congratulations to Jill Cole, University of Kentucky HealthCare Integrative Medicine and Health (USA), runner up in the ISCMR Dr. George Lewith Poster Prize for the best trainee posters at the 2022 International Congress on Integrative Medicine and Health.
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Dr. Marja Verhoef Methodology Lectureship

Jon Wardle (2022)
Published On 5/1/2022
Marja Verhoef ISCMR Lecture - Global Health Policy and Integrative Medicine
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Peter Wayne (2015)
Published On 5/15/2015
Marja Verhoef Lecture at the 2015 ICCMR (Jeju, South Korea)
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ISCMR Members Latest Research

Herbal Medicine for COVID-19: An Overview of Systematic Reviews and Meta-Analysis
Published On 6/3/2022
As coronavirus disease 2019 (COVID-19) continues to spread throughout countries, researchers and scientific groups have published a large number of scientific papers examining effective treatments and prevention strategies for COVID-19, including herbal medicine. It has become difficult to navigate the increasing volume of scientific material on the pandemic, and critical appraisal of these outcomes is needed. This overview of systematic reviews (SRs) aims to synthesize evidence from SRs and summarize the effects of herbal medicine interventions in the treatment of COVID-19.
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Skin Temperature of Acupoints in Health and Disease: A Systematic Review
Published On 6/1/2022
Despite substantial progress made in the field of acupuncture research, the existence and specificity of acupoints remain controversial. In recent years, the concept of acupoint sensitization has emerged as a theoretical framework for understanding acupoints as dynamic functional entities that are sensitized in pathological conditions. Based on this premise, some have claimed that specific acupoints are thermally distinct between healthy and clinical populations, but no systematic review has been conducted to synthesize and evaluate the quality of studies supporting such claims. In this review, we provide a summary and quality assessment of the existing literature addressing the question of whether changes in skin temperature at specific acupoints are indicative of pathological conditions.
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Lingguizhugan Decoction, A Chinese Herbal Formula, Improves Insulin Resistance in Overweight/Obese
Published On 5/31/2022
Lingguizhugan Decoction (LGZG) has been investigated in basic studies, with satisfactory effects on insulin resistance in non-alcoholic fatty liver disease (NAFLD). This translational approach aimed to explore the effect and underlying mechanism of LGZG in clinical setting. A randomized, double-blinded, placebo-controlled trial was performed.
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Characteristics and Outcomes of Herbal Medicine for Female Infertility: A Retrospective Analysis
Published On 5/28/2022
Few studies have assessed outcomes associated with the use of traditional medicine therapies to manage infertility in clinical practice. The aim of this study was to investigate the clinical characteristics of and infertility treatment effects among patients who visited a Korean medicine (KM) clinic to aid in achieving pregnancy. This study consisted of a 10-year analysis of patient records from a KM clinic.
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Acceptability of Pediatric Telerehabilitation Interventions Provided by Physical Therapists
Published On 5/27/2022
The purpose of this scoping review was to explore the available literature and identify gaps regarding the acceptability of telerehabilitation interventions provided by pediatric physical therapists and occupational therapists.
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Elicitation of Stakeholder Viewpoints About Medical Cannabis Research for Pain Management
Published On 5/26/2022
To determine acceptability of medical cannabis research in critically ill patients.
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Effects of Core Stability Training on Older Women with Low Back Pain: A Randomized Controlled Trial
Published On 5/23/2022
Studies have demonstrated that elderly people with low back pain (LBP) may have poor postural control compared to healthy older adults. Poor postural control is associated with poor balance performance and a high risk of serious falls. A variety of training strategies are proposed for LBP therapy, particularly core stabilization training. But this treatment for older people with LBP remains unclear.
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Effects of Tai Chi on Health Outcomes in Patients With Type 2 Diabetes Mellitus: A Systematic Review
Published On 5/21/2022
To explore the effects and dose–response relationship of Tai Chi for type 2 diabetes mellitus (T2DM) and to evaluate the methodological quality of the included trials and evidence quality of the outcomes.
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A Comprehensive Strategy Based on UPLC-Q/TOF-MS for the Identification of Compounds
Published On 5/19/2022
The aim of this study was to establish a comprehensive strategy based on liquid chromatography coupled with mass spectrometry to potently identify as many compounds of Chinese patent medicine as possible. Ultrahigh performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q/TOF-MS) was used to qualitatively analyze the Chinese patent medicine Xiao’er Chiqiao Qingre Granules (XCQG), which is recorded in the Chinese Pharmacopoeia.
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Exploring the Effects of Yoga Therapy on Heart Rate Variability and Patient-Reported Outcomes
Published On 5/19/2022
Following cancer treatment, adults commonly report worsened patient-reported outcomes (PROs) such as anxiety, stress, depression, persistent and upsetting cognitive complaints, unrelenting fatigue, and reduced quality of life. Poorer PROs are associated with disrupted autonomic nervous system functioning as measured by heart rate variability (HRV), both of which have been associated with greater morbidity and mortality. Interventions to improve HRV and PROs among adults following cancer treatment are needed. Yoga therapy holds promise as an intervention to improve HRV and PROs. Therefore, we conducted a single-subject exploratory experimental study to investigate the effects of yoga therapy on HRV and specific PROs (ie, cancer-related fatigue, anxiety, cognitive function, depression, stress, quality of life) in adults treated for cancer.
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Analysis on Medication Rules of Chinese Medicinal Herb Formulae in Uterine Subinvolution Treatment
Published On 5/16/2022
Uterine subinvolution, especially the subinvolution of the placental site, can be a life-threatening disease that induces secondary postpartum hemorrhage (PPH). Chinese Herbal Medicine has been widely used to improve postpartum recovery and treat uterine subinvolution for thousands of years. Yet, there are many potential laws hidden that are worth exploring.
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To “Tell or Not to Tell”—Exploring Disclosure About Medicine Use by People Living With Sleep
Published On 5/13/2022
To explore the difference in rates and reasons for disclosure of either conventional or complementary medicine (CM) to healthcare practitioners between people living with sleep disorders (SDs) and those without SDs.
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Knowledge Mobilization in the Canadian Naturopathic Community
Published On 5/12/2022
The process of applying new scientific knowledge to clinical decision-making is critical for the provision of optimal healthcare delivery; however, this process is often slow or inconsistent. Knowledge mobilization is the iterative and bidirectional process that involves the generation, dissemination, and translation of knowledge between researchers and knowledge users. Incorporation and application of knowledge mobilization in health care is being increasingly recognized across all fields, including naturopathic medicine. This review explores generally employed knowledge mobilization approaches. Additionally, it summarizes the knowledge mobilization strategies currently being used by the Canadian naturopathic profession and makes recommendations on the strategies which might be used in the future to bridge the gap between research evidence and clinical practice.
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Evaluation of the Quality of Online Patient Information at the Intersection of Complementary
Published On 5/10/2022
Hypertension impacts 1.1 billion people globally; many patients seek complementary and alternative medicine (CAM), as a result of adverse side effects from antihypertensive medications or because they believe natural options are safer. The internet is increasingly playing a role in patient health information-seeking behavior, however, the variability of information quality across websites is unclear. Thus, the purpose of this study was to assess the quality of websites providing consumer health information at the intersection of hypertension and CAM.
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Fuzi Decoction Ameliorates Pain and Cartilage Degeneration of Osteoarthritic Rats Through PI3K-Akt S
Published On 5/10/2022
Osteoarthritis (OA) is a difficult disease but the clinic lacks effective therapy. As a classic formula of traditional Chinese medicine (TCM), Fuzi decoction (FZD) has been clinically applied for treating OA-related syndromes, but its anti-OA efficacy and mechanism remain unclear.
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Improvement of Skin Wound Healing for Diabetic Mice with Thermosensitive Hydrogel Combined
Published On 5/7/2022
Chronic skin wound caused by diabetic disease is very common worldwide. Moreover, there is a shortage of effective curing technology in clinic. In this work, we developed a novel technology using thermosensitive hydrogel on wound top combined with insulin injection. The efficiency and mechanism of this technology were investigated in a diabetic mouse model.
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The Experience of Shiatsu for Care Partners and Persons Living With Dementia: a Qualitative Pilot
Published On 5/6/2022
Dementia is a progressive neurological condition that affects over 50 million people. It impacts quality of life for those diagnosed, their care partners, and the relationship between the two. Strategies to enhance quality of life and relationships are needed. Shiatsu may improve care partners’ well-being. Using touch through shiatsu may offer a meaningful way for care partners to interact with their partners living with dementia.
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Comparison of Flipped and Traditional Lecture-Based Classrooms for Kampo (Traditional Japanese
Published On 5/6/2022
Flipped classroom teaching (FC), one of the active learning methods, has been shown to be more effective than traditional lecture-based classroom teaching (TC) in a variety of fields. We have previously reported the usefulness of FC in a undergraduate 'Kampo Medicine (traditional Japanese medicine)' mandatory course, conducted in 2015. However, it was a pilot study and the results were based only on students' subjective evaluations.
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Dietary Supplements to Reduce Symptom Severity and Duration in People with SARS-Cov-2: Study Protoco
Published On 5/4/2022
COVID-19 has caused morbidity, hospitalisations and deaths worldwide. Despite four approved vaccines for COVID-19 in Canada, there is still a need for effective treatments, especially for people in the community. Vaccine efficacy is not 100% and long-term efficacy is still unknown. Furthermore, there are challenges to herd immunity including vaccine hesitancy and underlying conditions preventing vaccination. We aim to explore if the nutrients vitamin C, vitamin D, vitamin K2 and zinc are an effective treatment option for outpatients diagnosed with COVID-19. The primary outcome is the difference in participant-reported overall health; secondary outcomes include the effect on health status, symptom severity and duration, frequency and length of hospitalisations and mortality.
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Cancer-Related Fatigue in Patients Treated with Mistletoe Extracts: A Systematic Review
Published On 5/3/2022
Cancer-related fatigue remains one of the most prevalent and distressing symptoms experienced by cancer patients. Effective treatments for cancer-related fatigue are needed. The objective of this meta-analysis is to determine the impact of mistletoe extracts as a pharmacological treatment for the management of cancer-related fatigue.
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Pharmacists’ Perspectives on Traditional, Complementary, and Integrative Medicine in Japan
Published On 5/2/2022
Pharmacists guide patients in their use of traditional, complementary, and integrative medicine (TCIM). The present study aimed to evaluate the opinions of Japanese pharmacists regarding TCIM, and to evaluate the usability of the evidence-based Japanese Integrative Medicine (eJIM) website from the pharmacists’ point of view.
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Curcumin Alleviates Lipopolysaccharides-Induced Inflammation and Apoptosis in Vascular Smooth Muscle
Published On 5/1/2022
Curcumin plays an important role in inflammation regulation. This study aimed to investigate the effect of curcumin on vascular smooth muscle cells (VSMCs) inflammation induced by lipopolysaccharide (LPS) and its mechanism. VSMCs were treated with different concentrations of curcumin (0, 50, 100 and 150 μg/mL). MTT assay and flow cytometry were used to analyze the effects of curcumin on LPS-induced VSMCs viability and apoptosis. The expression and release of inflammatory cytokines in VSMCs were detected by real-time quantitative polymerase chain reaction (qRT-PCR) and enzyme-linked immunosorbent assay (ELISA).
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Salidroside Protects Against Osteoporosis in Ovariectomized Rats by Inhibiting Oxidative Stress and
Published On 4/30/2022
Osteoporosis (OP) is characterized as low bone mass, bone microarchitecture breakdown and bone fragility. The increase of oxidative stress could lead to breakdown in the balance of bone formation and resorption which gives rise to OP. Nrf2 is a transcription factor which takes part in oxidative stress and recently was reported that it can regulate the occurrence of OP. Salidroside (SAL) with the efficacies of anti-oxidation, anti-aging and bone-protection is one of the active ingredients in Ligustri Lucidi Fructus, a traditional Chinese medicinal herb. Nevertheless, few studies have explored the potential mechanism of SAL preventing OP development from the perspective of oxidative stress intervention.
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Serum Metabolomic Signatures of Plant-Based Diets and Incident Chronic Kidney Disease
Published On 4/30/2022
Greater adherence to plant-based diets is associated with a lower risk of incident chronic kidney disease (CKD). Metabolomics can help identify blood biomarkers of plant-based diets and enhance understanding of underlying mechanisms.
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Methodological Quality of Systematic Reviews on Chinese Herbal Medicine: A Methodological Survey
Published On 4/28/2022
Systematic reviews (SRs) synthesise the best evidence of effectiveness and safety on Chinese herbal medicine (CHM). Decision-making should be supported by the high-quality evidence of prudently conducted SRs, but the trustworthiness of conclusions may be limited by poor methodological rigour.
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Critical Evaluation of Specific Efficacy of Preparations Produced According to European Pharmacopeia
Published On 4/26/2022
European Pharmacopoeia monograph 2371 describes the production of homeopathic preparations. A specific efficacy of these preparations in high dilution levels is questionable in view of basic scientific principles. There is empirical evidence for such effects, for example in a Lemna-intoxication bioassay published 2010. To test the replicability and robustness of this bioassay, we conducted two experimental series (five independent blinded and randomised experiments each).
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Active Microbial Metabolites Study on Antitussive and Expectorant Effects and Metabolic Mechanisms
Published On 4/26/2022
A new method involving gut microbiota biotransformation, spectrum-effect relationship analysis and metabolomics analysis was developed to study the antitussive and expectorant microbial metabolites of platycosides fraction (MPFs) of Platycodonis Radix. Furthermore, their possible metabolic mechanisms were studied for the first time.
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Key Quality Factors for Chinese Herbal Medicines Entering the EU Market
Published On 4/23/2022
Chinese herbal medicines (CHMs) have unique advantages in the prevention and treatment of diseases, which are widely recognized in the world. More and more CHMs are becoming increasingly popular in the international markets. However, the quality control of CHMs is a significant issue for their acceptance and recognition in the international market. This review mainly focuses on the quality requirements for CHMs to enter the European Union (EU) market.
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Manipulation for Degenerative Lumbar Spondylolisthesis: A Systematic Review of Randomized Controlled
Published On 4/21/2022
To assess the effectiveness and safety of manipulation intervention for degenerative lumbar spondylolisthesis (DLS).
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Kampo Medicines for Supportive Care of Patients with Cancer: A Brief Review
Published On 4/19/2022
Kampo medicines, which are standardized traditional Japanese herbal medicines, have been tried to support patients with cancer.
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Fact or Fiction? The Role of Regulated Body-Identical Hormone Therapy for Menopausal Women
Published On 4/18/2022
Many menopausal women use hormone therapy, including regulated body-identical hormone therapy (rBHT), to relieve vasomotor symptoms and prevent cardiovascular disease. Despite growing interest in rBHT, there is uncertainty regarding potential benefits and risks. With this narrative review, we aimed to synthesize the literature regarding the efficacy of these therapies for managing vasomotor symptoms and preventing cardiovascular disease.
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Effect of Wuda Granule on Gastrointestinal Function Recovery After Laparoscopic Intestinal Resection
Published On 4/16/2022
Previous studies have suggested that the Wuda granule (WDG) could promote the recovery of gastrointestinal (GI) function after gynecologic abdominal surgery. This trial aimed to investigate the efficacy and safety of WDG in the rapid recovery of GI function in patients after laparoscopic intestinal resection in the setting of enhanced recovery after surgery (ERAS)-based perioperative care.
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The Medical Cannabis Regulatory Framework in Canada: A Narrative Review
Published On 4/16/2022
In 2001, Canada became one of the first countries to legalize medical cannabis; since then, the Canadian government has released policies regulating this product. In 2018, Canada passed the Cannabis Act to also legalize cannabis for recreational use and placed the previous medical cannabis regulatory framework under this same act. The purpose of this review is to provide a current account of the Canadian medical cannabis regulatory framework by examining patient access, ethical implications, and regulatory compliance.
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Protective Role of Wogonin Following Traumatic Brain Injury by Reducing Oxidative Stress
Published On 4/11/2022
Traumatic brain injury (TBI) is usually caused by accidental injuries and traffic accidents, with a very high mortality rate. Treatment and management following TBI are essential to reduce patient injury and help improve long‑term prognosis. Wogonin is a flavonoid compound with an antioxidant effect extracted from Scutellaria baicalensis Georgi.
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The Combination of Four Main Components in Xuebijing Injection Improved the Preventive Effects
Published On 4/9/2022
Acute graft-versus-host disease (aGVHD) is a major life-threatening complication after Allogeneic Hematopoietic Stem Cell Transplant (allo-HSCT). Although a series of immunosuppressant agents are routinely used as the first-line prevention, the morbidity and mortality rate remains high in allo-HSCT recipients.
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Capsaicin and Zinc Promote Glucose Uptake in C2C12 Skeletal Muscle Cells through a Common Calcium
Published On 4/7/2022
Capsaicin and zinc have recently been highlighted as potential treatments for glucose metabolism disorders; however, the effect of these two natural compounds on signalling pathways involved in glucose metabolism is still uncertain. In this study, we assessed the capsaicin- or zinc- induced activation of signalling molecules including calcium/calmodulin-dependent protein kinase 2 (CAMKK2), cAMP-response element-binding protein (CREB), and target of rapamycin kinase complex 1 (TORC1).
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Effectiveness of Integrative Chinese–Western Medicine for Chronic Kidney Disease and Diabetes
Published On 4/5/2022
Diabetes and chronic kidney disease (CKD) are pandemic, requiring more therapeutic options. This retrospective cohort evaluated the effectiveness, safety profile and prescription pattern of a pilot integrative medicine service program in Hong Kong. Data from 38 patients with diabetes and CKD enrolled to receive 48-week individualized add-on Chinese medicine (CM) were retrieved from the electronically linked hospital database. A 1:1 cohort was generated with patients from the same source and matched by propensity score.
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Efficacy of Persian Barley Water on Clinical Outcomes of Hospitalized Moderate-Severity COVID-19
Published On 4/3/2022
Coronavirus disease 2019 (COVID-19) is a debilitating disease with numerous medical and non-medical consequences. Our study aimed to evaluate the efficacy of Persian barley water in controlling the clinical outcomes of hospitalized COVID-19 patients.
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Interventions For Osteoarthritis Pain: A Systematic Review with Network Meta-Analysis of Existing
Published On 4/2/2022
To conduct a network meta-analysis comparing all treatments for osteoarthritis (OA) pain in the Cochrane Library.
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Complementary Medicine Use in Stroke Survivors: A US Nationally Representative Survey
Published On 4/1/2022
Stroke is the second most common cause of death worldwide. Even after surviving, long-term rehabilitation often becomes necessary and does not always lead to complete recovery. Guidelines focus on prevention of risk factors and present concepts for rehabilitation after a stroke. Additional to these recommendations, complementary medicine (CM) utilization is common among patients with neurological conditions. CM also offers a wide range of therapies for both prevention and rehabilitation in stroke. There is limited information available on CM utilization among stroke survivors and differences to patients without former stroke diagnosis.
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“Part of the Conversation”: A Qualitative Study of Oncology Healthcare Professionals’ Experiences
Published On 3/30/2022
The use of complementary medicine (CM) among individuals with cancer is common, however, it is infrequently assessed or documented by oncology healthcare professionals (HCPs). A study implementing standardized assessment and documentation of CM was conducted at a provincial cancer agency. The purpose of this study was to understand the perspectives and experience of oncology HCPs who took part in the study, as well as withdrew, regarding the feasibility and the challenges associated with assessment and documentation of CM use.
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An Assessment of Naturopathic Treatments, Health Concerns, and Common Comorbid Conditions
Published On 3/27/2022
Fibromyalgia (FM) is characterized by chronic pain, with allodynia and hyperalgesia being the most common signs. Many patients with FM explore, express interest, and use complementary and alternative medicine to help manage symptoms and improve quality of life. However, little is known about the clinical recommendations provided by naturopathic doctors (NDs).
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Neither the “Devil’s Lettuce” nor a “Miracle Cure:” The Use of Medical Cannabis
Published On 3/25/2022
Lack of guidance and regulation for authorizing medical cannabis for conditions involving the health and neurodevelopment of children is ethically problematic as it promulgates access inequities, risk-benefit inconsistencies, and inadequate consent mechanisms. In two virtual sessions using participatory action research and consensus-building methods, we obtained perspectives of stakeholders on ethics and medical cannabis for children and youth.
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Variation Determinants Within Massage Therapists’ Professional Identity
Published On 3/23/2022
Individuals have multiple, competing identities that vary in importance to the self. Professional identity is a way in which individuals attribute meaning to their contribution to society and is influenced by complex factors. Globally, the roles and responsibilities of massage therapists (MTs) vary, making it challenging to articulate a cohesive professional identity. This article describes the investigation into the variables which influenced response regarding MTs’ professional identity in Ontario, Canada.
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Safety of Chuna Manipulation Therapy in 289,953 Patients with Musculoskeletal Disorders
Published On 3/21/2022
Studies have reported that mild adverse events (AEs) are common after manual therapy and that there is a risk of serious injury. We aimed to assess the safety of Chuna manipulation therapy (CMT), a traditional manual Korean therapy, by analysing AEs in patients who underwent this treatment. Patients who received at least one session of CMT between December 2009 and March 2019 at 14 Korean medicine hospitals were included. Electronic patient charts and internal audit data obtained from situation report logs were retrospectively analysed.
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Development of the CLARIFY (CheckList stAndardising the Reporting of Interventions For Yoga)
Published On 3/19/2022
The use of yoga as a therapeutic modality is increasing; however, a lack of transparent intervention reporting is restricting the dissemination and implementation of yoga research into clinical and community practice. The aim of this study was to develop a yoga-specific reporting guideline as an extension to existing reporting guidelines for randomised controlled trials, observational studies and case reports.
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Complementary Medicine Use in US Adults with Hypertension: A Nationally Representative Survey
Published On 3/17/2022
As well as associated cardiovascular diseases (CVD) like heart attacks, stroke, or others, arterial hypertension shows rising incidence throughout the last decades. The risk of developing an elevated blood pressure is mostly based on environmental and behavioral factors. Therefore, guidelines usually base a first-line therapy on lifestyle modifications. Complementary medicine (CM) offers a wide range of therapies to support such and CM utilization is common among CVD. We sought to analyze CM utilization among participants particularly suffering from arterial hypertension and aimed to distinguish utilization rates of different therapy approaches and predicting factors on this part of health behavior.
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Korean Medicine Clinical Practice Guidelines for Lumbar Herniated Intervertebral Disc in Adults
Published On 3/16/2022
A significant number of individuals suffer from low back pain throughout their lifetime, and the medical costs related to low back pain and disc herniation are gradually increasing in Korea. Korean medicine interventions have been used for the treatment of lumbar intervertebral disc herniation.
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Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product
Published On 3/15/2022
Centella asiatica is reputed in Eastern medicine to improve cognitive function in humans. Preclinical studies have demonstrated that aqueous extracts of C. asiatica improve cognition in mouse models of aging and Alzheimer’s disease (AD) through the modulation of mitochondrial biogenesis and nuclear factor-erythroid-2-related factor 2 (Nrf2)-dependent antioxidant response genes.
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Chinese Herbal Medicine Treatment Based on Subgroup Differentiation as Adjunct Therapy
Published On 3/13/2022
Parkinson’s disease (PD) is a prevalent and debilitating condition. Conventional medications cannot control all symptoms and may inflict adverse effects. A survey reported that Chinese herbal medicine (CHM) is frequently sought. Existing CHM trials were contradictory and often of poor quality due to lack of methodological rigor. A national clinical guideline was drafted in China with diagnostic criteria and treatment strategy of Chinese medicine (CM) patterns subgroups of PD. The suggested CHM were found to exhibit neuroprotective effect in in vitro and in vivo studies. This trial aims to preliminarily assess the effect of CHM prescribed based on pattern differentiation on PD symptoms and patients’ quality of life, and evaluate the feasibility of the trial design for a future large-scale trial.
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A Survey of Patients Visiting an Ayurvedic Teaching Hospital for Factors Influencing the Decision
Published On 3/12/2022
In a pluralistic health care delivery model, it is important to assess whether the individual's health care choices are based upon evidences of efficacy and safety. Since the essence of medical pluralism lies in the fact that all such systems are equally accessible to a seeker, in such situation, it is highly relevant to check what defines such choices in real life.
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Detection and Risk Assessments of Multi-Pesticides in Traditional Chinese Medicine Chuanxiong
Published On 3/10/2022
With the internationalization of traditional Chinese medicines (TCMs) and the increasing use of herbal medicines around the world, there are concerns over their safety. In recent years, there have been some sporadic reports of pesticide residues in Chuanxiong Rhizoma (CX), although the lack of systematic and comprehensive analyses of pesticide residues and evaluations of toxicological risks in human health has increased the uncertainty of the potential effects of pesticides exposure in humans.
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Kimchi and Other Fermented Foods for Gastrointestinal Health
Published On 3/9/2022
This chapter introduces the health benefits of kimchi and other types of fermented foods in South Korea. It starts by presenting the types of Korean fermented foods and their fermentation methods, focusing on kimchi, doenjang, and cheonggukjang. It then explains the microbial compositions of all three fermented food and their health properties were discussed. The highlight of this chapter is the clinical evidence of Korean fermented food for gastrointestinal health. The chapter ends with the quality and safety of fermented food. A full literature review is performed to show the overall health benefits of fermented foods in Korea.
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Midwives’ Experiences of Caring for Women with Antenatal Anxiety and Depression: A Qualitative Study
Published On 3/8/2022
Pregnant women seek help for a range of physical and emotional pregnancy symptoms from traditional acupuncturists. Whether midwifery acupuncturists in Aotearoa New Zealand (Aotearoa NZ) provide acupuncture for antenatal anxiety and depression (AAD) in practice is currently unknown.
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Auricular Acupressure for Hemodialysis Patients with Insomnia: A Multicenter Double-Blind Randomized
Published On 3/5/2022
The effect of auricular acupressure (AA) for maintenance hemodialysis (MHD) patients with insomnia has been controversial. This study assessed the efficacy and safety of AA for MHD patients with chronic insomnia.
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Impact of the COVID-19 Pandemic on the Professional Identity of Massage Therapists:
Published On 3/4/2022
In late 2019, a pathogen outbreak occurred that rapidly spread, resulting in the coronavirus disease 2019 (COVID-19) global pandemic. Governments responded to the pandemic with a range of strategies, including forced quarantines and nationwide lockdowns. Research on professional identity during the pandemic has predominately focused on health care providers declared as “essential” rather than “nonessential.” In this study, the authors examine the impacts on the professional identity of massage therapists (MTs) who were predominately deemed as nonessential health care providers during the COVID-19 pandemic.
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Predictors of Headache/Migraine and the Use of Complementary Medicine in U.S. Children: A Population
Published On 3/3/2022
This study set out to determine the prevalence and possible risk factors of headache and/or migraine in U.S. children, as well as the prevalence of complementary medicine use in this population.
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Efficacy of Auricular Acupuncture and Lavender Oil Aromatherapy in Reducing Preinterventional
Published On 3/1/2022
Auricular acupuncture at the “relaxation point” and lavender oil aromatherapy can reduce preoperative anxiety associated with increased mortality and morbidity. Data on the effect of combined auricular acupuncture and lavender oil aromatherapy in patients undergoing cardiovascular interventions with the use of local anesthesia or under conscious sedation are sparse. The authors sought to evaluate the efficacy of auricular acupuncture and lavender oil aromatherapy in reducing preinterventional anxiety in cardiovascular patients.
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Exploring the Effects of Standardized Soft Tissue Mobilization on the Viscoelastic Properties
Published On 2/27/2022
Objectives of soft tissue mobilization applied to cesarean section (C-section) scars are to decrease stiffness and to reduce pain. Research investigating these effects is lacking.
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Comparison of Efficacy between Acupuncture Therapies in Improving Sacroiliac Joint Malposition:
Published On 2/25/2022
To provide available quantitative evidence of efficacy and safety of acupuncture treatments for improving sacroiliac joint malposition.
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Acupuncture and Electroacupuncture for Stroke: A Protocol for Overview of Systematic Review
Published On 2/23/2022
The aim of this study was to undertake a systematic overview of meta-analyses and published systematic reviews to identify whether and when acupunctureand electroacupuncture are deemed efficacious treatment options for stroke and stroke-related disorders.
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Safety, Effectiveness, and Professional Judgment: A Survey of Training-Related Perspectives Among
Published On 2/21/2022
Physiotherapists practise various forms of acupuncture worldwide, but no international consensus exists as to the appropriate duration of related training programs. In this cross-sectional study, we aimed to characterize the training-related backgrounds and views of acupuncture-practising physiotherapists.
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Is Acupuncture Effective for Knee Osteoarthritis? A Protocol for a Systematic Review
Published On 2/19/2022
Knee osteoarthritis (KOA) is one of the leading causes of disability. The effectiveness of acupuncture for treating KOA remains controversial. This protocol describes the method of a systematic review and meta-analysis evaluating the effectiveness and safety of acupuncture for treating KOA.
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Complementary and Alternative Medicine Mention and Recommendations in Guidelines for Anxiety
Published On 2/17/2022
Up to 43% of patients with anxiety disorders (ADS) use complementary and alternative medicine (CAM), however, many healthcare providers receive little training on this topic. Clinical practice guidelines (CPGs) are relied upon to guide decision-making, especially with respect to topics less familiar to healthcare providers. In the present study, we identified the quantity and assessed the quality of CAM recommendations in CPGs for the treatment and/or management of ADS.
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Pain, Disability, and MRI Changes in Lumbar Disc Herniation Patients Treated with Integrative
Published On 2/15/2022
To date, a 10-year follow-up study on complementary and alternative medical treatment of lumbar intervertebral disc herniation (LDH) has never been conducted. Therefore, we aimed to perform a prospective 10-year follow-up study on the integrated treatment of LDH in Korea.
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Profiles and Predictors of Healthcare Utilization: Using a Cluster-Analytic Approach to Identify
Published On 2/13/2022
The identification of typologies of health care users and their specific characteristics can be performed using cluster analysis. This statistical approach aggregates similar users based on their common health-related behavior. This study aims to examine health care utilization patterns using cluster analysis; and the associations of health care user types with sociodemographic, health-related and health-system related factors.
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Cognitive Behavioral Therapy for Migraine Headache: A Systematic Review and Meta-Analysis
Published On 2/9/2022
Migraine headaches are chronic neurological diseases that reduce the quality of life by causing severe headaches and autonomic nervous system dysfunction, such as facial flushing, nasal stuffiness, and sweating. Their major treatment methods include medication and cognitive behavioral therapy (CBT). CBT has been used for pain treatment and various psychogenic neurological diseases by reducing pain, disability, and emotional disorders caused by symptoms of mental illness and improving the understanding of mental health. This study aimed to evaluate the effectiveness and safety of CBT in treating migraines.
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Safety and Efficacy of Withania Compared with St John's Wort for the Treatment of Stress and Anxiety
Published On 2/5/2022
To compare the safety and efficacy of Withania somnifera (Withania) and Hypericum perforatum (St Johns wort, SJW) in the treatment of stress and anxiety in order to inform clinical practice.
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Demographics, Health Literacy and Health Locus of Control Beliefs of Australian Women Who Take
Published On 2/3/2022
Pregnant and breastfeeding women's use of complementary medicine products (CMPs) is common, and possibly associated with autonomous health care behaviours. However, the health literacy levels and health locus of control (HLOC) beliefs of women who use CMPs in pregnancy and lactation have not been previously assessed in a large Australian sample.
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Electroacupuncture for the Treatment of Frozen Shoulder: A Protocol for Systematic Review
Published On 2/1/2022
Electroacupuncture has been reported to successfully control pain. Currently, no systematic reviews of the effects of electroacupuncture on frozen shoulder patients have been performed. This review aims to provide current evidence on the efficacy of electroacupuncture for the management of pain in frozen shoulder.
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What are the Experiences of Patients Using Cannabis for Pain? A Systematic Review of Qualitative
Published On 1/31/2022
Cannabis is used by over 250 million individuals worldwide for a wide range of medical and recreational purposes. The most common health condition for which medicinal cannabis is used by patients is pain. To date, no review has summarized qualitative data from studies seeking to understand patients’ subjective experiences with cannabis for pain management, thus making this the objective of this systematic review.
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The Mediational Role of Social Support in the Relationship Between Stress and Antenatal Anxiety and
Published On 1/31/2022
Pregnancy can be a stressful period for most women and their family members, and the mental wellbeing of pregnant women can face serious challenges. Social support can play a role in improving the psychological well-being of pregnant women by enhancing the stress coping ability and alleviating stressful conditions. The current study aimed to assess the mediating effects of social support in the relationship between perceived stress and depressive symptoms as well as anxiety symptoms during pregnancy among Australian women.
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Teacher Plants — Indigenous Peruvian-Amazonian Dietary Practices as a Method for Using Psychoactives
Published On 1/25/2022
Indigenous groups of the Amazon have developed intricate methods for the application of psychoactives, among which particularly the dieta or diet method of Peruvian-Amazonian traditional medicine stands out. It is a retreat-like intervention involving lengthy periods of social, behavioural, and alimentary restrictions, while ingesting specially prepared plant substances. The interplay of the dietary conditions and plants ingested sensitizes the dieter to receive healing, strength, guidance, and knowledge. From a clinical scientific point of view, the method has remained largely underexplored, but seems more pertinent than ever given the increasing interest in Amazonian psychoactive preparations including ayahuasca (Banisteriopsis caapi) and the burgeoning field of psychedelic-assisted therapies in general.
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Transitioning to Practice: A Qualitative Investigation of Australian Graduate Naturopath’s
Published On 1/21/2022
The transition from student to practitioner can be challenging, resulting in stress, burnout and attrition. While there has been ample research examining graduate medical and allied health practitioner experiences of transitioning to practice, there is a paucity of research exploring such experiences in newly qualified naturopathic medicine practitioners. In light of this knowledge gap, the objective of this study was to ascertain the experiences of practicing as a naturopath in Australia within the first 5 years post-graduation.
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Experiences, Perceptions and Expectations of Health Services Amongst Marginalized Populations
Published On 1/16/2022
Poor health outcomes amongst marginalized groups result in part from health inequities related to social and structural determinants of health. Marginalized people report higher incidences of comorbidities, chronic disease and adverse health behaviours than their nondisadvantaged peers. The objective of this review is to examine marginalized Australians' experiences of and access to community-based primary health services in urban locations.
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Acupuncture for Cancer Pain: An Evidence-Based Clinical Practice Guideline
Published On 1/5/2022
This study aims to develop an evidence-based clinical practice guideline of acupuncture in the treatment of patients with moderate and severe cancer pain.
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Aromatherapy for Symptom Relief in Patients with Burn: A Systematic Review and Meta-Analysis
Published On 12/21/2021
This review aimed to provide an updated review of evidence regarding the effects of aromatherapy in relieving symptoms of burn injuries, focusing on pain and physiological distress.
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A Comparative Study of the Effectiveness of Pharmacopuncture Therapy for Chronic Neck Pain
Published On 12/21/2021
This two-arm, parallel, pragmatic, multicenter, clinical randomized, controlled trial with a 12-week follow-up period aimed to compare the effectiveness of pharmacopuncture therapy and physical therapy strategies for chronic neck pain.
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Extracts of Gynura procumbens could treat nanodiethylnitrosamine-induced mouse liver cancer
Published On 12/14/2021
Gynura procumbens (Lour.) Merr, (Family Asteraceae), which serves as both medicine and food in traditional ethnic medicine, has the effects of diminishing inflammation, relieving cough, reducing blood glucose and lipids levels, mitigating hepatotoxicity, and can be used for liver cancer prevention and treatment. Aim of the study: To explore how the ethanol extract of Gynura procumbens stems (EEGS) can effectively intervene in the tumor microenvironment, it is necessary to study the mechanism of EEGS on the chemical toxicant nanodiethylnitrosamine (nanoDEN) that induces liver cancer.
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A Preliminary Study of the Effects of Mindfulness-Based Cognitive Therapy on Structural Brain
Published On 11/26/2021
Mindfulness-based cognitive therapy for children (MBCT-C), as a psychotherapeutic intervention, has been shown to be effective for treating mood dysregulation (MD). While previous neuroimaging studies of MD have reported both pre-treatment structural and functional alterations, the effects of MBCT-C on brain morphological network organisation has not been investigated.
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A Cannabidiol-Containing Alginate Based Hydrogel as Novel Multifunctional Wound Dressing
Published On 11/24/2021
In addition to preventing infection and promoting angiogenesis, novel hydrogel dressings are highly expected to possess the potential to scavenge reactive oxygen species (ROS) and reduce inflammatory responses during the wound healing process.
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Acupuncture for Amnestic Mild Cognitive Impairment: A Pilot Multicenter, Randomized, Parallel
Published On 11/19/2021
Patients with amnesic mild cognitive impairment (aMCI) are more likely to develop Alzheimer disease than corresponding age normal population. Because Alzheimer disease is irreversible, early intervention for aMCI patients seems important and urgent. We have designed a pilot multicenter, randomized, parallel controlled trial to assess the efficacy and safety of acupuncture on aMCI, explore the feasibility of acupuncture in the treatment of aMCI, so as to provide a reference for large-sample clinical trials in the next stage.
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A Precision-Preferred Comprehensive Information Extraction System for Clinical Articles
Published On 11/16/2021
This study established a precision-preferred system specially designed for the data extraction of traditional Chinese medicine (TCM) articles, providing foundational data for subsequent clinical article analysis and synthesis of TCM clinical evidence.
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Acupuncture on Vascular Cognitive Impairment Associated with Cerebral Small Vessel Disease
Published On 8/1/2021
Cerebral small vessel disease (CSVD) is the most common cause of vascular cognitive impairment (VCI). Acupuncture has been used as a treatment approach to alleviate the symptoms caused by VCI. The aim was to conduct a systematic review and meta-analysis to evaluate the efficacy of acupuncture on VCI associated with CSVD.
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